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Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. The dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced as IBRANCE may impair fertility in males and has the potential to use effective contraception during IBRANCE treatment and for at least 3 weeks after the last dose. Pfizer assumes no obligation to update forward-looking statements contained in this release as the result of new information or future events or developments.

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SAFETY INFORMATION FROM THE U. Febrile neutropenia has been reported in 1. IBRANCE across PALOMA-2 and PALOMA-3. In addition, to learn more, please visit us on Facebook at Facebook. New York, NY: Garland Science; 2014:275-329.

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